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Glossing over the game breakers

The real world has some unfortunate limits which have the potential to restrict the "flow" of a game.

These are some pretty big things which do have serious consequences for a game, so they are often discussed as to why breaks in theses rules are allowed or not allowed.

I'm going to break them down as I see them by their closest link to science. I've thought of three so far (I'm not sure if there are any others of the same "magnitude" as these however). Most of them ultimately have to do with time compression (not waiting days, months, years, decades for things to happen).

Biological Sciences
Healing
Healing is one of those things that often gets glossed over. Honestly if people took damage like they did in games, it would probably takes weeks or months to get back to normal, yet in most games, a little bandaging goes a long way to making a character all healed up. "Get back in there!"

Physical Sciences
Speed of Light travel
The Speed of light is not just a good idea, it's the law. But if we can't travel FTL, how can we realistically explore space in a game? "Engage warp drives"

Social Sciences
Language
In many instances, the language barrier will halt communication between groups of people for quite some time. Who wants to wait while interpreters on each side haltingly figure out each other's language over the course of several adventurers? "The babel fish is an amazing discovery"

I'm not saying that either course (ignoring or enforcing these limits) is right or wrong, it's just that it seems that these are often brought as touchstones in discussions of games.

Can you think of any others?